Can antiVEGF treatment for wet AMD lead to worsening dry AMD?

A lack of diffusible VEGF growth factor (i.e. one that can reach other cells at a distance when secreted) can cause degeneration fo the choriocapillaris a retinal defect similar to non-exudative, or “dry” age-related macular degeneration (AMD), according to a study in the November 3, 2009 print addition of Proceedings of the National Academy of Sciences. This means that the continuous blockage of VEGF may contribute to the development or worsening of the “dry” form of AMD.

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